Non-steroidal anti-inflammatory drugs (NSAIDs) and organ damage: A current perspective

Non-steroidal anti-inflammatory drugs (NSAIDs) and organ damage: A current perspective

Category: Side Effects

Biochemical Pharmacology

Long considered wonder drugs, available over the counter and very inexpensively worldwide, NSAIDs such as aspirin, acetaminophen and naproxen are to treat everything from headaches to sprained ankles and heart disease. However, there’s increasing evidence of serious health risks associated with long-term use and in combination use with other prescription and OTC medications. This survey of clinical studies conducted in leading institutions around the world points to significant clinical evidence of a host of serious impairment of major organ functionality including dementia, stroke and heart failure that should lead to greater efforts by regulators and practitioners to educate and caution consumers.

… data from multiple placebo-controlled trials and meta-analyses studies alarmingly signify the adverse effects of NSAIDs in gastrointestinal, cardiovascular, hepatic, renal, cerebral and pulmonary complications.

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